Assessment of Gastroesophageal Junction

Dedifferentiated Liposarcoma of the Gastroesophageal Junction.

Liposarcoma is one of the most common sarcomas in adults, but very rarely presents as a primary in the upper gastrointestinal system. Herein, we present a 71-year-old male patient who underwent wedge excision biopsy twice and then fine needle aspiration and total gastrectomy for a recurrent gastroeosophageal junction mass. In microscopic sections, both well-differentiated and dedifferentiated c...

Gastroesophageal Junction Pathology: Diagnostic and Controversial Issues

Therapeutic approaches to gastroesophageal junction adenocarcinomas.

The following, from the 12th OESO World Conference: Cancers of the Esophagus, includes commentaries on the distinction between adenocarcinomas above, below, or within the gastroesophageal junction; combined modality therapy; tumor markers for use in personalized medicine; PET-CT and endoscopic biopsies in the evaluation of response to neoadjuvant chemoradiation therapy; a standardized grading s...

Relevance of Position and Movement of the Gastroesophageal Junction in Gastroesophageal Reflux Disease

TO THE EDITOR: Gastroesophageal reflux disease (GERD) and its complications are increasingly recognized in many parts of Asia, largely due to an increasing prevalence of obesity. Obese subjects are found to have frequent transient lower esophageal sphincter (LES) relaxations (TLESRs) and more likely to reflux with underlying mechanisms being unclear. Besides the circular muscle, recent evidence...

Relevance of Position and Movement of the Gastroesophageal Junction in Gastroesophageal Reflux Disease: Author's Reply

TO THE EDITOR: I appreciate the interest and comments on our paper, which was published in the July 2013 issue of this journal. As you have commented, hiatus hernia is an important factor in the pathogenesis of gastroesophageal reflux disease (GERD). Especially, the elderly patients with GERD have high possibility for accompanying hiatus hernia. Our study was performed in 9 patients with GERD a...